Volatile Composition of Juniperus pingii var. wilsonii and Its Inhibitory Effect on Nitric Oxide Production of Macrophage Cells was written by Zhu, Mengxia;Ling, Lijun;De, Ji;Lu, Yan;Chen, Daofeng. And the article was included in Journal of Essential Oil-Bearing Plants in 2018.Quality Control of Isopentyl 3-methylbutanoate This article mentions the following:
The leaves and twigs of Juniperus pingii var. wilsonii (Cupressaceae) smell aromatic and are traditionally used as the Tibetan medicine Xuba. Their essential oil obtained by ultrasonic-assisted hydrodistillation and volatiles collected by GC headspace technique were analyzed and compared by GC-MS. The analyses revealed the presence of thirty-nine components in the essential oil, representing 95.8% in content of the total oil, mainly including sabinene (22.6%), elemol (15.5%) and (-)-terpinen-4-ol (9.6%). Thirty-eight components accounting for 99.4% of the headspace volatiles were identified, mainly including sabinene (32.5%), β-pinene (21.9%) and α-thujene (10.3%). The compositions of the oil and headspace volatiles were quite similar, and twenty-five compounds identified were in common, which was 91.3% of the oil and 96.0% of the headspace volatiles in content. The essential oil could obviously inhibit Nitric oxide production in LPS-stimulated RAW 264.7 cells with no significant effect on cell viability, indicating its good anti-inflammatory activity. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Quality Control of Isopentyl 3-methylbutanoate).
Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of Isopentyl 3-methylbutanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics