Copper-Catalyzed Enantioselective Friedel-Crafts Alkylation of Pyrrole with Isatins was written by Li, Chong;Guo, Fengfeng;Xu, Kun;Zhang, Sheng;Hu, Yanbin;Zha, Zhenggen;Wang, Zhiyong. And the article was included in Organic Letters in 2014.Related Products of 2199-49-7 This article mentions the following:
The highly enantioselective Friedel-Crafts alkylation of pyrrole with isatins catalyzed by the tridentate Schiff base/Cu catalyst was developed. Hexafluoroisopropanol (HFIP) was used as a crucial additive to improve the enantioselectivity. In the case of N-unprotected isatins, an innovative substrate slow-releasing strategy was applied by virtue of a Henry/retro-Henry reaction. In the experiment, the researchers used many compounds, for example, Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7Related Products of 2199-49-7).
Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Related Products of 2199-49-7
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics