Denny, William A. et al. published their research in Mutation Research, Fundamental and Molecular Mechanisms of Mutagenesis in 1990 | CAS: 14667-47-1

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: Methyl 2-aminonicotinate

Structure-activity relationships for the mutagenic activity of tricyclic intercalating agents in Salmonella typhimurium was written by Denny, William A.;Turner, Pamela M.;Atwell, Graham J.;Rewcastle, Gordon W.;Ferguson, Lynnette R.. And the article was included in Mutation Research, Fundamental and Molecular Mechanisms of Mutagenesis in 1990.Recommanded Product: Methyl 2-aminonicotinate This article mentions the following:

A total of 25 different tricyclic DNA-intercalating chromophores bearing a common -CONH(CH2)2NMe2 solubilizing side-chain were compared with the classical frameshift mutagen 9-aminoacridine for their ability to induce revertants in S. typhimurium strain TA1537 (sensitive to frameshift mutation by acridine mutagens). The compounds showed varying levels of activity in this strain. For the fused linear and fused angular tricyclics, activity varied from zero to similar levels to 9-aminoacridine, but with no discernable relationship between activity and either structure or the measured physico-chem. properties. However, the 2-1 tricyclic compounds had essentially no mutagenic activity. Since several of these compounds have high in vivo antitumor activity, this is useful knowledge. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1Recommanded Product: Methyl 2-aminonicotinate).

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: Methyl 2-aminonicotinate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics