Physiological activity of Chinese lichen (Gyrophora esculenta) component, methyl 2,4-dihydroxy-6-methylbenzoate and the related compounds was written by Wu, Shuhsien;Zhao, Zhendong;Okada, Yoshiharu;Watanabe, Yoshiyuki;Takahata, Toshiyuki;Inoue, Toshio;Otsubo, Eiji;Wang, Jing;Lu, Yanju;Nomura, Masato. And the article was included in Asian Journal of Chemistry in 2014.Quality Control of Methyl 4-Hydroxy-2-methoxybenzoate This article mentions the following:
It was confirmed that there was a higher expression of antioxidant potential in Me 2,4-dihydroxy-6-methylbenzoate (orsellinic acid Me ester) (2), which was isolated from methanol extract oil of Chinese lichen Gyrophora esculenta rather than from commercialized ascorbic acid. Taking this into account, 4 types of compounds-(4-7) which are known to be related to compound (2)-have been synthesized by using 2,4-dihydroxy benzoic acid (3) as starting material. After that, some physiol. activity tests on these compounds have been conducted in the following aspects: antioxidant potential, cytotoxicity, cytokine suppressant effect and histamine liberation inhibition and the effects have been evaluated, resp. The result shows that (2) and Me 2,4-dihydroxybenzoate (4) showed high radical expression in both antioxidant potential and histamine liberation inhibition. It was also found that none of these compounds expresses cytotoxicity. In the experiment, the researchers used many compounds, for example, Methyl 4-Hydroxy-2-methoxybenzoate (cas: 28478-46-8Quality Control of Methyl 4-Hydroxy-2-methoxybenzoate).
Methyl 4-Hydroxy-2-methoxybenzoate (cas: 28478-46-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Quality Control of Methyl 4-Hydroxy-2-methoxybenzoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics