Two Competitive but Switchable Organocatalytic Cascade Reaction Pathways: The Diversified Synthesis of Chiral Acetal-Containing Bridged Cyclic Compounds was written by Lv, Xue-Jiao;Chen, Ying-Han;Liu, Yan-Kai. And the article was included in Organic Letters in 2019.Related Products of 33166-79-9 This article mentions the following:
β-Keto esters such as Et benzoylacetate underwent α-oxidation with mCPBA followed by base-mediated Michael addition to hydroxy- or amino-substituted cinnamaldehydes such as trans-o-hydroxycinnamaldehyde, cyclization in the presence of a proline-derived silyl ether, and acetalization in the presence of BF3·Et2O to yield methanobenzodioxepines such as I. The sequence avoids the isolation of unstable α-hydroxy-β-keto esters which oxidize to diketo esters on attempted isolation. Reaction of β-keto esters and hydroxy-substituted cinnamaldehydes with omission of mCPBA under similar conditions and yielded benzodioxocinecarboxylates such as II. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Related Products of 33166-79-9).
Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 33166-79-9
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics