Construction of Bridged Aza- and Oxa-[n.2.1] Skeletons via an Intramolecular Formal [3 + 2] Cycloaddition of Aziridines and Epoxides with Electron-deficient Alkenes was written by Xing, Siyang;Wang, Yuhan;Jin, Changkun;Shi, Shaochen;Zhang, Yihui;Liao, Ziya;Wang, Kui;Zhu, Bolin. And the article was included in Journal of Organic Chemistry in 2022.Quality Control of malonic acid dibutyl ester This article mentions the following:
An intramol. formal [3+2] cycloaddition of activated aziridines and epoxides with electron-deficient alkene I (X = N,O; R1 = Me, Et, n-Pr, i-Pr, n-bu, Bn; R3 = H, F, Cl; R4 = H, OMe, CF3; R5 = H, Me; R2 = 4-Br6H4, 4-NO2C6H4, C6H5) has been developed for the general and efficient construction of bridged aza- and oxa-[n.2.1] (n = 3,4) II skeletons. The strategy can be promoted by lithium iodide efficiently. In order to demonstrate its potential, the intramol. formal [3 + 2] cycloaddition was used to access the important intermediate of homoepiboxidine. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Quality Control of malonic acid dibutyl ester).
malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Quality Control of malonic acid dibutyl ester
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics