Synthesis and x-ray structure of stable 2H-isoindoles was written by Murashima, Takashi;Tamai, Ryuji;Nishi, Keiji;Nomura, Kentaroh;Fujita, Ken-ichi;Uno, Hidemitsu;Ono, Noboru. And the article was included in Perkin 1 in 2000.Computed Properties of C7H8N2O4 This article mentions the following:
Stable 2H-isoindoles with electron-withdrawing groups were prepared by reaction of meta-dinitrobenzenes with isocyanoacetate in the presence of DBU. The use of MeCN as the solvent or a phosphazene base (BTPP) as a non-ionic base improved the yields. The structure was confirmed by x-ray crystallog. anal. of tert-Bu 7-cyano-5-nitro-2H-isoindole-1-carboxylate. According to the x-ray anal., this substance existed in the solid phase only as the 2H-isomer. In the experiment, the researchers used many compounds, for example, Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7Computed Properties of C7H8N2O4).
Ethyl 4-nitro-1H-pyrrole-2-carboxylate (cas: 5930-92-7) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Computed Properties of C7H8N2O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics