Synthesis of substituted porphyrins was written by Cheng, D. O.;LeGoff, Eugene. And the article was included in Tetrahedron Letters in 1977.Application of 2199-49-7 This article mentions the following:
3,4-Disubstituted pyrroles with HCHO and HCl or HBr in EtOH at reflux for several h then standing exposed to air for a few days to several weeks gave porphyrins unsubstituted in the meso positions. E.g., 3,4-dimethylpyrrole with HCHO and HBr gave 76% I (R = R1 = Me). Similarly, 3-acetyl-4-ethylpyrrole gave a mixture of 3 isomers of I (R, R1 = MeCO, Et) which on B2H6 reduction gave I (R = R1 = Et). In the experiment, the researchers used many compounds, for example, Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7Application of 2199-49-7).
Ethyl 4-methyl-1H-pyrrole-3-carboxylate (cas: 2199-49-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 2199-49-7
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics