Enantioselectivity of Pseudomonas cepacia lipase for the acetylation of 2-hydroxy carboxylic acid esters was written by Sundholm, Oskari;Kanerva, Liisa T.. And the article was included in ACH – Models in Chemistry in 1998.Formula: C11H14O3 This article mentions the following:
Structurally different Et or Me 2-hydroxy carboxylates were resolved by Pseudomonas cepacia lipase-catalyzed acetylations with vinyl acetate in di-Et ether. One type of the alc. substrates (2-hydroxy-2-arylacetates and 2-hydroxy-3-arylpropionates) contained a hydroxy group at the stereocenter. These compounds were resolved with high enantioselectivity (ee 91-99%) at ca. 50% conversion. The other alc. substrates [threo-2-hydroxy-3-methylbutyrate and threo- or erythro-2-hydroxy-3-aryl-3-arylthio(or aryloxy)propionates] with two stereocenters generally resulted in enantiopure products, and the reactions stopped at 50% conversion. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Formula: C11H14O3).
Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Formula: C11H14O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics