Fracchiolla, Giuseppe et al. published their research in Journal of Medicinal Chemistry in 2009 | CAS: 15399-05-0

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: Ethyl 2-hydroxy-3-phenylpropanoate

New 2-Aryloxy-3-phenyl-propanoic Acids As Peroxisome Proliferator-Activated Receptors α/γ Dual Agonists with Improved Potency and Reduced Adverse Effects on Skeletal Muscle Function was written by Fracchiolla, Giuseppe;Laghezza, Antonio;Piemontese, Luca;Tortorella, Paolo;Mazza, Fernando;Montanari, Roberta;Pochetti, Giorgio;Lavecchia, Antonio;Novellino, Ettore;Pierno, Sabata;Conte Camerino, Diana;Loiodice, Fulvio. And the article was included in Journal of Medicinal Chemistry in 2009.Name: Ethyl 2-hydroxy-3-phenylpropanoate This article mentions the following:

The preparation of a new series of 2-aryloxy-3-phenyl-propanoic acids, resulting from the introduction of a linker into the di-Ph system of the previously reported PPARα/γ dual agonist 1, allowed the identification of new ligands with improved potency on PPARα and unchanged activity on PPARγ. For the most interesting stereoisomers I [X = CH2, CH2CH2], X-ray studies in PPARγ and docking experiments in PPARα provided a mol. explanation for their different behavior as full and partial agonists of PPARα and PPARγ, resp. Due to the adverse effects provoked by hypolipidemic drugs on skeletal muscle function, we also investigated the blocking activity of I on skeletal muscle membrane chloride channel conductance and found that these ligands have a pharmacol. profile more beneficial compared to fibrates currently used in therapy. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Name: Ethyl 2-hydroxy-3-phenylpropanoate).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: Ethyl 2-hydroxy-3-phenylpropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics