Angibaud, Patrick et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2010 | CAS: 173341-02-1

tert-Butyl (morpholin-2-ylmethyl)carbamate (cas: 173341-02-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Synthetic Route of C10H20N2O3

Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors was written by Angibaud, Patrick;Van Emelen, Kristof;Decrane, Laurence;van Brandt, Sven;ten Holte, Peter;Pilatte, Isabelle;Roux, Bruno;Poncelet, Virginie;Speybrouck, David;Queguiner, Laurence;Gaurrand, Sandrine;Marien, Ann;Floren, Wim;Janssen, Lut;Verdonck, Marc;van Dun, Jacky;van Gompel, Jacky;Gilissen, Ron;Mackie, Claire;Du Jardin, Marc;Peeters, Jozef;Noppe, Marc;Van Hijfte, Luc;Freyne, Eddy;Page, Martin;Janicot, Michel;Arts, Janine. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2010.Synthetic Route of C10H20N2O3 This article mentions the following:

Pursuing our efforts in designing 5-pyrimidylhydroxamic acid anti-cancer agents, we have identified a new series of potent histone deacetylase (HDAC) inhibitors. These compounds exhibit enzymic HDAC inhibiting properties with IC50 values in the nanomolar range and inhibit tumor cell proliferation at similar levels. Good solubility, moderate bioavailability, and promising in vivo activity in xenograft model made this series of compounds interesting starting points to design new potent HDAC inhibitors. In the experiment, the researchers used many compounds, for example, tert-Butyl (morpholin-2-ylmethyl)carbamate (cas: 173341-02-1Synthetic Route of C10H20N2O3).

tert-Butyl (morpholin-2-ylmethyl)carbamate (cas: 173341-02-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Synthetic Route of C10H20N2O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics