Facile Construction of Troponoid Derivatives Incorporating Imidazolin-2-one Moieties was written by Yu, Jing;Chen, Xiaobei;Liu, Ye;Wu, Bing;Li, Haiyan;Hu, Yanwei;Wang, Liang;Zhang, Shilei. And the article was included in Synthesis in 2020.Quality Control of 3-Cyanophenylisocyanate This article mentions the following:
Troponoid derivatives incorporating imidazolin-2-one moieties I [R = 4-Me, 3-F, 3-CF3-4-Cl, etc.] were efficiently constructed via a cascade process, under simple thermal conditions, which features a novel nitrogen source, is catalyst- and oxidant-free and was high atom- and step-economy. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Quality Control of 3-Cyanophenylisocyanate).
3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Quality Control of 3-Cyanophenylisocyanate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics