A Unified and Desymmetric Approach to Chiral Tertiary Alkyl Halides was written by Zheng, Yin;Zhang, Suihan;Low, Kam-Hung;Zi, Weiwei;Huang, Zhongxing. And the article was included in Journal of the American Chemical Society in 2022.Computed Properties of C10H11FO2 This article mentions the following:
A suite of dinuclear zinc catalysts with a prolinol- or pipecolinol-derived tetradentate ligand reductively desymmetrized a large collection of easily available halomalonic esters to α-halo-β-hydroxyesters were reported. These polyfunctionalized tertiary alkyl fluorides, chlorides, and bromides proved to be useful intermediates toward fluorinated drug analogs and polyhalogenated monoterpenes. The facile intramol. epoxidation of the chiral chloride and bromide products was enabled an expeditious access to natural products containing tertiary alc. motifs. In the experiment, the researchers used many compounds, for example, Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2Computed Properties of C10H11FO2).
Ethyl 2-(4-fluorophenyl)acetate (cas: 587-88-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Computed Properties of C10H11FO2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics