Synthesis and Preliminary Screening of O-β-D-Galactopyranosides as Potential Mimic of UDP-Galp against Mycobacterium tuberculosis was written by Mugunthan, G.;Sriram, Dharmarajan;Yogeeswari, Perumal;Kartha, K. P. Ravindranathan. And the article was included in Journal of Carbohydrate Chemistry in 2012.Computed Properties of C8H4N2O This article mentions the following:
O-Galactopyranosides, e.g. I, were synthesized as potential mimics of uridine diphosphate galactopyranose (UDP-Galp), which is the substrate of the mutase enzyme involved in the mycobacterial cell wall biosynthesis by converting UDP-Galp to UDP-Galf. In vitro assay against the Mycobacterium tuberculosis H37Rv strain gave promising results with min. inhibitory concentration (MIC) values in the range of 3.13 to 25 μg/mL. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Computed Properties of C8H4N2O).
3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Computed Properties of C8H4N2O
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics