Selective cyclization of alkynols and alkynylamines catalyzed by potassium tert-butoxide was written by Li, Deng Yuan;Shi, Ke Ji;Mao, Xiao Feng;Zhao, Zheng Le;Wu, Xin Yan;Liu, Pei Nian. And the article was included in Tetrahedron in 2014.Synthetic Route of C13H15NO2 This article mentions the following:
Potassium tert-butoxide (t-BuOK) was found to be an effective catalyst for the cyclization of aromatic alkynols and alkynylamines. In the presence of 10 mol % t-BuOK, a range of alkynols were converted to the corresponding exo-cyclic enol ethers as pure Z-stereoisomers with 100% selectivity and moderate to excellent yields. Moreover, the cyclization of alkynylamines was also achieved to afford indoles and isoindolin-1-ones in good yields. In the experiment, the researchers used many compounds, for example, tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3Synthetic Route of C13H15NO2).
tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Synthetic Route of C13H15NO2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics