Preparation of doubly responsive polymer functionalized silica hybrid nanoparticles via a one-pot thiol-isocyanate click reaction at room temperature was written by Ou, Baoli;Huang, Rao;Zhou, Hu;Li, Zhengfeng;Chen, Lijuan;Zhou, Zhihua;Li, Duxin. And the article was included in Polymer Composites in 2017.Safety of Benzyl benzodithioate This article mentions the following:
Well-defined poly(N-isopropylacrylamide) and poly(2-(diethylamino) Et methacrylate) were synthesized first by a reversible addition-fragmentation chain transfer process. These polymers were then reduced to generate an end thiol group to react with isocyanate groups on the surface of silica nanoparticles, which were pretreated with toluene-2,4-diisocyanate, by a one-pot “click” reaction to prepare temperature and pH responsive polymer functionalized hybrid silica nanoparticles. The polymer functionalized silica hybrid nanoparticles were characterized by a range of techniques such as Fourier transform IR spectroscopy and dynamic light scattering. The doubly responsive polymer functionalized silica hybrid nanoparticles show both temperature and pH responsive behavior and their solution properties were dependent on the ratio of the two polymers on the surface of silica. Covalent functionalization of the silica nanoparticle with well-defined temperature and pH responsive polymers was accomplished via a one-pot thiol-isocyanate click reaction. This reaction was found to be extremely efficient in producing doubly responsive polymer functionalized silica hybrid nanoparticle, even at relatively low reaction temperature and short reaction time. Thermogravimetric anal. indicated that the same ratio of poly(N-isopropylacrylamide) and poly(2-(diethylamino)ethyl methacrylate) functionalized silica hybrid nanoparticle consisted of 42.46 wt% polymer. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Safety of Benzyl benzodithioate).
Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of Benzyl benzodithioate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics