Divergent Dynamic Kinetic Resolution of a Racemic Mixture of Four Stereoisomers via N-Heterocyclic Carbene Organocatalysis was written by Vasamsetty, Laxmaiah;Kong, Xiangwen;Meng, Miao;Yang, Shuang;Xu, Weici;Reddy, Pogula Sreekanth;Fang, Xinqiang. And the article was included in Chemistry – An Asian Journal in 2018.Product Details of 13669-10-8 This article mentions the following:
Racemic mixtures of four stereoisomers are easily formed via many fundamental organic transformations, but the direct utilities of these mixtures were less studied and remain large challenges to date. The authors introduce a new method, i.e., divergent dynamic kinetic resolution, to achieve the separation of racemic mixtures of four stereoisomers. The hypothesis was proved by using a N-heterocyclic carbene-catalyzed benzoin reaction, which afforded two separable diastereomeric products bearing three consecutive stereocenters with good to excellent enantioselectivities. The authors believe that this resolution protocol will find applications in more transformations. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8Product Details of 13669-10-8).
Ethyl 3-oxo-3-(thiophen-2-yl)propanoate (cas: 13669-10-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 13669-10-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics