Mohamed, Marwa Abd El Hameed published the artcileProtective effects of Saraca indica L. leaves extract (family Fabaceae) against gamma irradiation induced injury in the kidney of female albino rats, COA of Formula: C11H22O2, the main research area is Saraca indica Fabaceae leaf extract kidney gamma irradiation; GC-MS; Saraca indica L.; flavonoids; inflammation; irradiation.
This work was designed to estimate the protective effect of Saraca indica L. leaves ethanolic exract against γ-irradiation induced renal damage in rats. Phytochem. examinations of S. indica L. leaves extract resulted in the separation of three flavanone glycosides: Astilibin (1), Neoastilbin (2), and Eriodictyol-7-O-α-L-rhamnopyranoside (3); two flavonols: Quercetin (4) and Quercetin-3-O-α-L-arabinopyranosyl-(1′′′-6′′)-O-β-D-galactopyranoside (5) in addition of Gallic acid (6) and Me gallate (7). Their structures elucidated by chem. evidences and spectroscopic anal. (1 and 2D-NMR, -ESI-MS, UV). Female rats were used and classified into: control, Ext (200 mg/kg body wt/day orally for 7 days), IRR (8Gy), Ext + IRR, and Sily+IRR groups (received silymarin 50 mg/kg b.wt orally as reference drug). Results showed that S. indica L. leaves extract ameliorated the kidney function tests, hs-CRP, IL-1β, ACE, TNF-α, GSH, and MDA as well as, decreased the histopathol. changes of kidney. In conclusion, S. indica L. leaves extract had a renoprotective activity against irradiation induced renal injury due to its flavononid contents.
Environmental Toxicology published new progress about Apoptosis. 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, COA of Formula: C11H22O2.
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