Ahmad, Imtiaz published the artcileGC-MS profiling, phytochemical and biological investigation of aerial parts of Leucophyllum frutescens (Berl.) I.M. Johnst (Cenizo), Application In Synthesis of 929-77-1, the main research area is Leucophyllum type II diabetes phytochem antidiabetic antimicrobial erythrocyte hemolysis.
Leucophyllum frutescens (Berl.) I. M. Johnst has been used as a crude drug for treating various respiratory ailments, dysentery, cataract and liver disorders in the folk medicine systems by the inhabitants of America and Mexico. The Phytochem. and biol. investigation was established by spectrophotometrically and chem. profiling was performed by GC-MS anal. The chem. profiling by GC-MS anal. revealed that HELE majorly contains 9-octadecenoic acid (Z)-, Me ester, pentadecanoic acid, 14-methyl-, Me ester, 2,6-bis(3,4-methylenedioxyphenyl)-3,7-dioxabicyclooctane, (+)-sesamin, 9,12-octadecadienoic acid, Me ester, 9,12,15-octadecatrienoic acid, Et ester, (Z,Z,Z)-, n-hexadecanoic acid, hexadecanoic acid, Et ester, phytol, Me stearate, cyclohexanone, 1H,3H-Furo[3,4-c]furan, 1,4-bis(3,4-dimethoxy phenyl)tetrahydro-, [1R-(1.alpha.,3a.alpha.,4.alpha.,6a.alpha.)]-, and squalene. Strong inhibition of α-glucosidase and urease enzymes was observed by HELE (IC50 0.3321 mg.mL-1) and CHLE (IC50 4.711 mg.mL-1) extracts, resp. Phytochem. quantification revealed high TPC by BULE (189.369±1.393 mg GA.Eq.gm-1 DE ± S.D) and high TFC by CHLE (232.458±1.589 mg Qu.Eq.gm-1 DE ± S.D). CHLE presented with highest antioxidant content equivalent to Trolox, by five different spectrophotometric methods such as TAA, DPPH, TEAC, FRAP, and CUPRAC. The study concludes that L. frutescens possesses significant antioxidant, antidiabetic and cytotoxic activities indicating that L. frutescens as a potential candidate for discovery of novel phytochem. products and industrial applications.
South African Journal of Botany published new progress about Antidiabetic agents. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Application In Synthesis of 929-77-1.
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