Dekel, Amir published the artcileThe sulcatone receptor of the strict nectar-feeding mosquito Toxorhynchites amboinensis, Computed Properties of 111-11-5, the main research area is Toxorhynchites sulcatone receptor Or4 gene; Aedes aegypti; Insect repellent; Odorant receptor; Olfaction; Toxorhynchites amboinensis.
Controlling Ae. aegypti populations and the prevention of mosquito bites includes the development of monitoring, repelling and attract-and-kill strategies that are based on understanding the chem. ecol. of these pests. Olfactory-mediated attraction to mammals has recently been linked to the mosquito Aedes aegypti odorant receptor Or4, which is activated by animal-released 6-Methyl-5-hepten-2-one (sulcatone). This odorant is also a major component of flower scents and may play a role outside animal-host seeking. To explore the role of this chem. cue, we looked at the interaction between sulcatone and an Or4 homolog expressed in the antennae of the strict nectar-feeding mosquito Toxorhynchites amboinensis. Using the two-electrode voltage clamp of Xenopus oocytes as a heterologous expression system, we show that this receptor is a high intensity sulcatone receptor comparable to its Aedes counterparts. We also show that OR4 is activated by other aliphatic ketones and is inhibited by DEET. This pharmacol. characterization suggests that sulcatone may be operating in more than one context in the Culicidae family.
Insect Biochemistry and Molecular Biology published new progress about Aedes aegypti Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Computed Properties of 111-11-5.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics