Comparative experimental study of acute toxicity and gastric tolerance of eterylate, benorylate and acetylsalicylic acid was written by Alonso, S.;Armijo, M.;Pina, M.. And the article was included in Archivos de Farmacologia y Toxicologia in 1978.Category: esters-buliding-blocks The following contents are mentioned in the article:
In acute (10-day) toxicity studies in mice, eterylate (I) [62992-61-4] was 2- and 2.5-fold less toxic than benorylate (II) [5003-48-5], and acetylsalicylic acid (III) [50-78-2], resp.; all 3 compounds were administered orally. In chronic (4- and 24-wk) toxicity studies with the same 3 compounds, the order of toxicity was III > II > I. I was the best tolerated compound with respect to ulcerogenesis. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Category: esters-buliding-blocks).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Category: esters-buliding-blocks
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics