Topological modeling of analgesia was written by Mathur, K. C.;Gupta, Sunita;Khadikar, P. V.. And the article was included in Bioorganic & Medicinal Chemistry in 2003.Name: 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:
Analgesic activity (log IC) of a large series of 97 analgesics was modeled topol. using a series of distance-based topol. indexes. The results show that analgesic activity (log IC) exhibit inter familial correlation and these can only be modeled by splitting 97 analgesics into five different categories. The regression analyses of the data show that the Wiener (W)-, branching (B)- and first-order connectivity (χ)- indexes are the better topol. indexes for modeling the activity (log IC), and that the W index gave excellent results. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Name: 4-Acetamidophenyl 2-acetoxybenzoate).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Name: 4-Acetamidophenyl 2-acetoxybenzoate
Referemce:
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