Optimization of synthesis process of benorilate was written by Ma, Yan. And the article was included in Huagong Shikan in 2014.Computed Properties of C17H15NO5 The following contents are mentioned in the article:
The purpose of the research is to optimize the synthesis process of benorilate by designing orthogonal test using esterification reaction solvent, esterification time and phase transfer catalyst as single factors. The influence degree of esterification reaction solvent, esterification time and phase transfer catalyst to the yield of benorilate is: solvent >time >phase transfer catalyst. The best combination on synthesis of benorilate was as follows: using benzene as solvent, esterification time of 1.5h, and using tetrabutylammonium bromide as phase transfer catalyst. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Computed Properties of C17H15NO5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C17H15NO5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics