Synthesis and characterization of a new series of thiadiazole derivatives as potential anticancer agents was written by Cevik, Ulviye Acar;Osmaniye, Derya;Levent, Serkan;Saglik, Beguem Nurpelin;Cavusoglu, Betuel Kaya;Oezkay, Yusuf;Kaplancikl, Zafer Asim. And the article was included in Heterocyclic Communications in 2020.HPLC of Formula: 2253-73-8 The following contents are mentioned in the article:
The aim of this study was to determine the capacity of newly synthesized 1,3,4-thiadiazole compounds I [R = Me, allyl, Ph, etc.] as chemotherapeutic agents. The structures of the obtained compounds were elucidated using 1H-NMR, 13C-NMR and mass spectrometry. Although the thiadiazole derivatives I did not prove to be significantly cytotoxic to the tumor tissue cultures, compound I [R = phenyl] showed activity against the C6 rat brain cancer cell line (IC50 0.097 mM) at the tested concentrations This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8HPLC of Formula: 2253-73-8).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 2253-73-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics