Study of the inhibition of platelet aggregation provoked by etherylate, benorylate and its molecular components in comparison with acetylsalicylic acid was written by Ortega, P.;Alonso, S.;Navarro, J. L.. And the article was included in Archivos de Farmacologia y Toxicologia in 1978.Reference of 5003-48-5 The following contents are mentioned in the article:
In vitro platelet aggregation was inhibited by eterylate (I) [62992-61-4] to a greater extent than by benorylate [5003-48-5] or acetylsalicylic acid [50-78-2]. In rats given a single dose of I the inhibition of platelet aggregation induced by ADP was 2 times greater than that of rats treated with acetylsalicylic acid, whereas in rats given 7 doses of either drug the inhibition of platelet aggregation by I was 1.2 times that observed in rats treated with acetylsalicylic acid. When the inducing agent was collagen the activity of both drugs was equal. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Reference of 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Reference of 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics