4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides in the synthesis of a new heterocyclic [1,2,3]triazolo[4,5-e][1,4]thiazepine system was written by Syrota, Natalia A.;Kemskiy, Sergiy V.;Bol’but, Andriy V.;Chernobaev, Igor I.;Liavinets, Oleksandr S.;Vovk, Mykhailo V.. And the article was included in Chemistry of Heterocyclic Compounds in 2021.Synthetic Route of C4H7NS The following contents are mentioned in the article:
4-(N-Boc-amino)-1H-1,2,3-triazolecarbothioamides I [R1 = Me, Ph, 2-MeOC6H4, H2CH2CPh; R2 = Et, i-Pr, t-Bu, cyclohexyl] , obtained by a sequential treatment of 4-(N-Boc-amino)-1H-1,2,3-triazoles with n-BuLi and alkyl isothiocyanates at -78 and -60°C, reacted with Et bromoacetate, forming the resp. 4-(N-Boc-amino)-5-thioimidates II , which underwent intramol. cyclocondensation upon treatment in saturated HCl solution in dioxane, producing 8-(alkylimino)-4,8-dihydro-1H-[1,2,3]triazolo[4,5-e][1,4]thiazepin-5(6H)-ones III. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Synthetic Route of C4H7NS).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C4H7NS
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics