Camelio, Andrew M. et al. published their research in Journal of Organic Chemistry in 2022 | CAS: 2253-73-8

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of Isopropylisothiocyanate

Gram Scalable Method to Synthesize Biscarbodiimides and Asymmetric Monocarbodiimides: A Platform to Access an Array of Phosphaguanidines, Amidines, and Guanidines was written by Camelio, Andrew M.;Krasovskiy, Arkady;Bailey, Brad;Davis, Anna. And the article was included in Journal of Organic Chemistry in 2022.Safety of Isopropylisothiocyanate The following contents are mentioned in the article:

A mild, broadly functional group tolerant methodol. has been developed to access a variety of mono- and bis-carbodiimides RN=C=NR1 (R = i-Pr, cyclohexyl, adamantan-1-yl, etc.; R1 = Bn, cyclohexyl) and RN=C=N(CH2)5N=C=NR in good yield and high purity on multigram scale. Direct addition into these versatile motifs facilitated the rapid synthesis of a library of novel amidinines, guanidines, and phosphaguanidines RNHC(R2)=NR1 (R2 = diphenylphosphanyl, 9H-carbazol-9-yl, diethylaminyl, etc.) and RN=C(R2)NH(CH2)nNHC(R2)=NR (n = 4, 5). This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Safety of Isopropylisothiocyanate).

Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of Isopropylisothiocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics