H2O2-Mediated Synthesis of 1,2,4-Thiadiazole Derivatives in Ethanol at Room Temperature was written by Cao, Xian-Ting;Zheng, Zuo-Ling;Liu, Jie;Hu, Yu-He;Yu, Hao-Yun;Cai, Shasha;Wang, Guannan. And the article was included in Advanced Synthesis & Catalysis in 2022.COA of Formula: C4H7NS The following contents are mentioned in the article:
Herein, the H2O2-mediated synthesis of 1,2,4-thiadiazole derivatives under metal-free conditions at room temperature with ethanol as the sole solvent was reported. Various substrates could undergo the reaction smoothly, providing the expected yields of the desired products. Moreover, the target products were obtained by filtration or extraction instead of column chromatog., which requires a large amount of organic solution and silica gel during purification The developed synthetic method can be potentially applied in the large-scale preparation of 1,2,4-thiadiazole derivatives as agrochems., pharmaceuticals, and functional materials. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8COA of Formula: C4H7NS).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C4H7NS
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics