Synthesis, characterization, biological evaluation, and computational study of benzimidazole hybrid thiosemicarbazide derivatives was written by Acharya, Prachi T.;Bhavsar, Zeel A.;Jethava, Divya J.;Rajani, Dhanji P.;Pithawala, Edwin;Patel, Hitesh D.. And the article was included in Journal of Heterocyclic Chemistry.Product Details of 2253-73-8 The following contents are mentioned in the article:
The antimicrobial, antitubercular, antimalarial, and antioxidant properties of a series of benzimidazole hybrid thiosemicarbazide derivatives I (R = H, tert-Bu, cyclohexyl, Ph, 2-MeOC6H4, etc., R1 = NO2, Br) were investigated in vitro. The majority of the compounds studied have excellent antibacterial and antioxidant properties. In addition, an in silico investigation was conducted. By calculating ADME-Tox descriptors, all freshly synthesized mols. were shown to have outstanding pharmacokinetic properties, indicating that these derivatives could be used as a basis for the development of some novel active drugs. The SAR (structure-activity relationship) was also briefly described. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Product Details of 2253-73-8).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 2253-73-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics