Olefin-Oriented Selective Synthesis of Linear and Branched N-Alkylated Heterocycles by Hydroamination was written by Sushmita;Aggarwal, Trapti;Saini, Kapil Mohan;Verma, Akhilesh K.. And the article was included in European Journal of Organic Chemistry in 2020.Formula: C4H7NS The following contents are mentioned in the article:
An effective base-induced selective approach for the synthesis of linear and branched N-alkylated heterocycles by hydroamination of olefins has been described. The designed C-N bond formation method was directed through the olefin, as with styrenes only linear N-alkylated product was obtained, and acrylates gave linear as well as branched alkylated heterocycles. This protocol provided the synthesis of exclusive N-alkylated product instead of the C-3 Michael addition product. The reaction was also compatible with Ph vinyl sulfone, thus leading to the formation of sulfone substituted heterocycles in good yield. Further, the method was utilized for the synthesis of medicinally important analogs of CB1 Cannabinoid receptor and Dimebon analog in short reaction sequence. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Formula: C4H7NS).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C4H7NS
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics