Prodrugs to Codrugs was written by Gangrade, Deepali;Karande, Ravindra. And the article was included in Current Drug Therapy in 2017.Product Details of 5003-48-5 The following contents are mentioned in the article:
A review. Background: The Carrier linked prodrug as per literature is known to be a pharmacol. inactive chem. derivative and could be used to change the physicochem. properties of compounds Codrugs is a type of carrier linked prodrug, and consist of two usually synergistic drugs or moieties attached to each other. Objective: synthesis of codrug consists of two pharmacol. active compounds coupled together where one drug is the carrier for the other and vice versa. Result: It is a very beneficial area of research and its admittance in human therapy has given successful results clin. as well as therapeutically. Conclusion: The emphasis is carried on Benorylate, the Codrug of aspirin and paracetamol for improved anti-inflammatory and analgesic activity. The article also takes a review of the various applications of Codrugs and the development in this field during the last few decades. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Product Details of 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Product Details of 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics