Ruzi, Rehanguli’s team published research in Nature Communications in 11 | CAS: 1877-71-0

Nature Communications published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, Product Details of C9H8O4.

Ruzi, Rehanguli published the artcileUpgrading ketone synthesis direct from carboxylic acids and organohalides, Product Details of C9H8O4, the publication is Nature Communications (2020), 11(1), 3312, database is CAplus and MEDLINE.

A photoredox, nickel and phosphoranyl radical synergistic cross-electrophile coupling of com. available chems., aromatic acids RCO2H (R = 4-methylphenyl, thiophen-3-yl, naphthalen-2-yl, etc.) and aryl/alkyl bromides R1Br (R1 = 6-(trifluoromethyl)pyridin-3-yl, 2-cyanoethyl, quinolin-3-yl, etc.) was reported. This allows for concise synthesis of highly functionalized ketones RC(O)R1directly, without the preparation of activated carbonyl intermediates or organometallic compounds, and thus complements the conventional Weinreb ketone synthesis. Use of the appropriate photocatalyst, ligand amount and solvents can match the reaction rate required by any simple catalytic cycle. The practicality and synthetic robustness of the reaction are illustrated by the facile synthesis of complex ketones from readily available feedstock chems.

Nature Communications published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, Product Details of C9H8O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics