Hepatoprotective effects of Moringa oleifera Lam (Moringaceae) leaf extracts in streptozotocin-induced diabetes in rats was written by Muzumbukilwa, Willy Tambwe;Nlooto, Manimbulu;Owira, Peter Mark Oroma. And the article was included in Journal of Functional Foods in 2019.Synthetic Route of C10H20O2 The following contents are mentioned in the article:
Effects of methanolic leaf extracts of Moringa oleifera (MO) on hepatic injury in streptozotocin (STZ)-induced diabetes were investigated. Male Wister rats were divided into 6 groups (n = 7). Animals in group A were orally treated daily with 3.0 mL/kg/body weight (BW) of distilled water, while B, E and F were similarly treated with 500, 250 and 500 mg/kg/BW of MO, resp. Groups C-F were rendered diabetic by single i.p. injections of 45 mg/kg/BW of STZ. Addnl., group D was treated with s.c. insulin (2.0 U/kg/BW, bid). Diabetic animals exhibited significant weight loss, polydipsia, impaired glucose tolerance, fasting hypoinsulinemia and impaired liver function tests compared to controls. Treatment with MO methanolic leaf extracts significantly improved weight loss, polydipsia, glucose tolerance and also liver function tests in diabetic animals. MO has dose-dependent antidiabetic and hepatoprotective effects. This study involved multiple reactions and reactants, such as Octyl acetate (cas: 112-14-1Synthetic Route of C10H20O2).
Octyl acetate (cas: 112-14-1) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C10H20O2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics