Design, synthesis, and biological evaluations of (E)-2-(1-[2-mercapto-4-methyl-1-phenyl-1H-imidazol-5-yl]ethylidene)hydrazinecarbothioamide derivatives as antimicrobial agents was written by Daraji, Drashti G.;Rajani, Dhanji P.;Jayanthi, Sivaraman;Patel, Hitesh D.. And the article was included in Journal of Heterocyclic Chemistry in 2022.Related Products of 2253-73-8 The following contents are mentioned in the article:
Imidazole derivatives I [R = H, 2-OH, 2-Cl, etc.; R1 = H, benzyl, 4-chlorobenzyl, etc.; R2 = H, i-Pr, Ph, etc.] were synthesized using the microwave irradiation method and were characterized using spectral anal. techniques such as proton NMR, mass and Fourier transform IR spectroscopy. All the analogous I were assessed for their in-vitro antimicrobial activity and in-silico; min. inhibition concentration values of some conjugates were evaluated against extended spectrum beta-lactamases, vancomycin-resistant enterococci, and Methicillin-resistant Staphylococcus aureus strains from clin. samples. All the analogous I were used as ligands in mol. docking and adsorption, distribution, metabolism and excretion against saDHPS. Furthermore, compounds I were also examined for their in-vitro antituberculosis and antimalarial activity. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Related Products of 2253-73-8).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Related Products of 2253-73-8
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics