Enantiomeric synthesis of natural alkylglycerols and their antibacterial and antibiofilm activities was written by Fernandez Montoya, Deicy J.;Contreras Jordan, Luis A.;Moreno-Murillo, Barbara;Silva-Gomez, Edelberto;Mayorga-Wandurraga, Humberto. And the article was included in Natural Product Research in 2021.Name: Methyl nonadecanoate The following contents are mentioned in the article:
Alkylglycerols (AKGs) are bioactive natural compounds that vary by alkyl chain length and degree of unsaturation, and their absolute configuration is 2S. Three AKGs were synthesized in enantiomerically pure form, and were characterized for the 1st time together with 12 other known and naturally occurring AKGs. Their structures were established using 1H and 13C APT NMR with 2D-NMR, ESI-MS, or HRESI-MS and optical rotation data, and they were tested for their antibacterial and antibiofilm activities. Some AKGs showed activity against 5 clin. isolates and Pseudomonas aeruginosa ATCC 15442, with MIC values in the range of 15-125μg/mL. In addition, at half of the MIC, most of the AKGs reduced Staphylococcus aureus biofilm formation in the range of 23-99% and P. aeruginosa ATCC 15442 biofilm formation in the range of 14-64%. The antibiofilm activity of the AKGs assessed in this work had not previously been studied. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Name: Methyl nonadecanoate).
Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Name: Methyl nonadecanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics