Surfactant based nanoreactor micellar assembly: An innovative route for synthesis of 2-thioxo-2,3-dihydroquinazolin-4(1H)-ones was written by Patil, Mayuri V.;Mhaldar, Pradeep M.;Tayade, Shivaji N.;Rashinkar, Gajanan S.;Pore, Dattaprasad M.. And the article was included in Journal of Molecular Liquids in 2022.Synthetic Route of C4H7NS The following contents are mentioned in the article:
An innovative route for synthesis of 2-thioxo-2,3-dihydroquinazolin-4(1H)-ones using isatoic anhydride and Ph isothiocyanate via in-situ formation of anthranilic acid was described. The reaction was performed in the nano-micellar assembly of surfactant, 4-(dimethylamino)-1-hexadecylpyridinium hydroxide [DAHP]+[OH]– as a nano-reactor. The micelle concentration of surfactant is found to be 0.002 mol.dm-3 using the conductivity data. The micellar particle dimensions were demonstrated from small-angle X-ray scattering (SAXS) anal. viz. micelle diameter and the interspacing between two micelles which were found to be 14.8 nm and 2.6 nm, resp. From the TGA anal., the surfactant is thermally stable up to 250°C with 76.01% weight loss. The practical simplicity, atom economy, good to high yields, ease of product isolation and purification, water as eco-benign solvent and catalyst recyclability were the remarkable aspects of the present methodol. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Synthetic Route of C4H7NS).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C4H7NS
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics