Using design of experiments to fabricate nanostructured lipid carrier of egg white hydrolysates was written by Jangpromma, Nisachon;Jearranaiprepame, Supisara;Nowichai, Boonpob;Sosiangdi, Sirinthip;Khunkitti, Watcharee. And the article was included in Songklanakarin Journal of Science and Technology in 2022.Product Details of 31566-31-1 The following contents are mentioned in the article:
The aims of this study were to develop a nanostructured lipid carrier (NLC) system and optimize an appropriate NLC formulation using design of experiments (DOE). The results showed that the formulation containing glycerol monostearate (GMS) 0.35 g, stearic acid (SA) 0.50 g and iso-Pr myristate (IPM) 0.65 g was optimal with entrapment efficiency (%EE) (59.21%), particle size (233.7nm) and zeta potential (-41.26 mV). Moreover, solid lipid (GMS, SA) and liquid lipid (IPM) had significant impact on NLC characteristics. The pos. effect on the %EE was due to the interaction between GMS and IPM, and SA and IPM. The optimal formulation EWH-NLC at concentration 125 μg/mL expressed the highest inhibitory activity against NO production in RAW 264.7 macrophages with no cytotoxicity. The release profile of EWH-NLC in the cream base exhibited sustained release behavior that best fitted with Higuchi model. These results suggest that the NLC is a suitable carrier for EWH in topical application with a sustained-release profile. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Product Details of 31566-31-1).
Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 31566-31-1
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics