In-source CID mass spectral libraries for the “general unknown” screening of drugs and toxicants was written by Marquet, P.;Venisse, N.;Lacassie, E.;Lachatre, G.. And the article was included in Analusis in 2001.Related Products of 5003-48-5 The following contents are mentioned in the article:
A “general unknown” screening procedure for drugs and toxicants using LC-ES-MS was developed. It involved in-source collision induced dissociation (CID) of the mol. ions (in the neg.-ion mode) or protonated mols. (in the pos.-ion mode) generally obtained from electrospray sources. Spectra were reconstructed by adding, on one hand, a pair of pos. spectra, one without and one with fragmentation, and on the other a pair of neg. spectra acquired in similar conditions. These reconstructed spectra showed at least as many fragments as MS/MS spectra, and sometimes as many as electron-ionization spectra. They were repeatable and reproducible enough to be used for the specific identification of hundreds of mols. Libraries of about 1100 pos. spectra and 500 neg. spectra were constructed and are used routinely, together with chromatog. separation involving a Nucleosil C18, 5 μm column (150 × 1 mm i.d.) and a gradient of acetonitrile in 2 mM, pH 3 ammonium formate as a screening technique complementary to GC-MS and HPLC-DAD. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Related Products of 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Related Products of 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics