Alkattan, Rana’s team published research in Dental Materials in | CAS: 10287-53-3

Dental Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Application of Ethyl 4-dimethylaminobenzoate.

Alkattan, Rana published the artcileA multi-functional dentine bonding system combining a phosphate monomer with eugenyl methacrylate, Application of Ethyl 4-dimethylaminobenzoate, the publication is Dental Materials, database is CAplus and MEDLINE.

The tooth-resin composite interface is frequently associated with failure because of microbial contamination, hydrolytic and collagenolytic degradation Thus, designing a dentin bonding system (DBS) with an intrinsically antimicrobial polymerisable monomer is of significance especially if it can be used with self-etching primers enabling resistance to degradation of the interface.Exptl. adhesives were developed incorporating eugenyl methacrylate (EgMA) at concentrations of 0,10 or 20 wt%, designated as EgMA0, EgMA10 and EgMA20, resp., for use as a two-step self-etch DBS with the functional monomer bis[2-(methacryloyloxy) ethyl] phosphate (BMEP) in the primer. The curing, thermal and wettability properties of the adhesives were determined, and hybrid layer formation was characterised by confocal laser scanning microscopy, microtensile bond strengths (μTBS) and nanoleakage by back-scattered SEM. In situ zymog. was used to assess MMP inhibitory activity of the BMEP-EgMA DBS.EgMA in the adhesives lowered the polymerization exotherm and resulted in higher Tg, without neg. affecting degree of conversion. Water sorption and solubility were significantly lower with higher concentrations of EgMA in the adhesive. The formation of a distinct hybrid layer was evident from confocal images with the different adhesives, while EgMA20 yielded the highest μTBS post water storage challenges and lowest nanoleakage after 6 mo. The exptl. DBS exhibited minimal to no MMP activity at 3 mo.The hydrophobic nature of EgMA and high cross-link d. exerts considerable benefits in lowering water uptake and polymerization exotherm. The application of EgMA, adhesives in conjunction with BMEP in a multi-functional self-etching DBS can resist MMP activity, hence, enhance longevity of the dentin-resin composite interface.

Dental Materials published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Application of Ethyl 4-dimethylaminobenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics