Molecular spectroscopic study on site-selective binding of benorilate to bovine serum albumin was written by Zhang, Yan-zheng;Chen, Fang;Wang, Ya-dan;Zhang, Yin-tang;Huang, Ju;Chen, Yan;Ye, Bao-xian;Xu, Mao-tian. And the article was included in Faguang Xuebao in 2012.Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:
The interaction between benorilate (BEN) and bovine serum albumin (BSA) was investigated under physiol. condition by mol. spectroscopic techniques, including fluorescence spectroscopy, UV-visible spectroscopy, synchronous fluorescence spectroscopy and three-dimensional fluorescence spectroscopy. The intrinsic fluorescence of tryptophan in BSA was significantly quenched by BEN via dynamic quenching. The hydrophobic interaction did favor the interaction of BSA with BEN. The apparent binding constants and binding sites number at the tryptophan site were 1 050 L · mol-1 and 0.88, resp. Thermodn. parameters such as enthalpy change (ΔH), entropy change (ΔS) and free energy change (ΔG) were also obtained. The conformation changes of BSA in the presence of BEN were proved by the evidences of synchronous fluorescence spectroscopy and three-dimensional fluorescence spectroscopy. Two site-specific fluorescence probes, dansylamide (DA) and dansyl-L-proline (DP), were employed in competitive binding experiments to monitor the BEN binding sites of BSA. The apparent binding constants at site I and II were 4 300 and 21 200 L · mol-1, resp. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate
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