LC-MS detection of valuable or toxic ingredients and 48 chemical drugs added into Dahuoluo pills and Tongren Dahuoluo pills was written by Hu, Qing;Zhong, Jiqiang;Mao, Xiuhong;Wang, Ke;Ji, Shen. And the article was included in Yaowu Fenxi Zazhi in 2010.Name: 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:
Sep. specific methods by LC/MSn for the identification of 3 valuable or toxic ingredients and 48 analgesic and anti-inflammatory chem. drugs added illegally into Dahuoluo pills and Tongren Dahuoluo pills were established. The detection of 48 compounds was performed by Agilent 1100 HPLC/MSD trap using Agilent ZORBAX SB-C18 (2.1 mm × 150 mm, 5 μm) column as stationary phase and 0.5% formic acid solution-methanol system as mobile phase. The gradient elution was done with as flow rate of 0.3 mL/min-1. The detection of 3 valuable and toxic ingredients was performed by the same instrument and stationary phase, using water acetonitrile system in gradient elution as mobile phase. Pos. and neg. ionization switch autoscan mode was adopt using ESI source. Samples were extracted by Ultrasonic with methanol. Comparing with retention time and spectra of references in library set up by ourselves, the target compounds in sample are screened and identified. There were ephedrine detected in 229 samples, hyodeoxycholic acid detected in 41 samples, and loureirin B detected in 71 samples. The methods were accurate, fast and sensitive. It was the first time in China to report the LC/MS method, which could evaluate the quality of samples objectively. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Name: 4-Acetamidophenyl 2-acetoxybenzoate).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Name: 4-Acetamidophenyl 2-acetoxybenzoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics