Magnetic graphene based dispersive micro-solid-phase extraction coupled with liquid chromatography-tandem quadrupole mass spectrometry for analysis of nine non-steroidal anti-inflammatory drugs in livestock and poultry meat was written by Dong, Chanchan;Hu, Yanyun;Lu, Yaning;Song, Wei;Han, Fang;Zheng, Ping;Deng, Ning. And the article was included in Sepu in 2016.Product Details of 5003-48-5 The following contents are mentioned in the article:
A novel anal. method was developed for the determination of nine non-steroidal anti-inflammatory drugs (NSAIDs) in meat samples by magnetic graphene nanocomposite (Fe3O4-G) based on dispersive micro-solid-phase extraction (μ-SPE) coupled with liquid chromatog.-mass spectrometry detection. Samples were homogenized and extracted with acidified acetonitrile. After defatting with the high speed frozen centrifugation, the sample solutions were defatted with n-hexane followed by μ-SPE. Some important parameters influencing the extraction efficiency including the extraction time, the pH value of sample solution and the elution conditions were optimized. The limits of detection (LODs, S/N = 3) of the nine NSAIDs ranged from 0.2 to 8.2 μg/kg, and the limits of quantification (LOQs, S/N = 10) ranged from 0.5 to 25.4 μg/kg. The average recoveries were 83.3%-104.5% with the relative standard deviations between 1.2% and 6.8% obtained from samples spiked at LOQ, 2LOQ and 10LOQ levels. Compared with Sep-Pak Vac NH2 and Oasis HLB cartridges, Fe3O4-G had excellent purification effect, high loading amounts and good reusability. The results demonstrate that the method provide a novel pretreatment technique for the determination of NSAID residues in meat samples. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Product Details of 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics