Single-chain heteropolymers transport protons selectively and rapidly was written by Jiang, Tao;Hall, Aaron;Eres, Marco;Hemmatian, Zahra;Qiao, Baofu;Zhou, Yun;Ruan, Zhiyuan;Couse, Andrew D.;Heller, William T.;Huang, Haiyan;Olvera de la Cruz, Monica;Rolandi, Marco;Xu, Ting. And the article was included in Nature (London, United Kingdom) in 2020.Related Products of 26662-94-2 The following contents are mentioned in the article:
Precise protein sequencing and folding are believed to generate the structure and chem. diversity of natural channels1,2, both of which are essential to synthetically achieve proton transport performance comparable to that seen in natural systems. Geometrically defined channels have been fabricated using peptides, DNAs, carbon nanotubes, sequence-defined polymers and organic frameworks3-13. However, none of these channels rivals the performance observed in their natural counterparts. Here we show that without forming an atomically structured channel, four-monomer-based random heteropolymers (RHPs)14 can mimic membrane proteins and exhibit selective proton transport across lipid bilayers at a rate similar to those of natural proton channels. Statistical control over the monomer distribution in an RHP leads to segmental heterogeneity in hydrophobicity, which facilitates the insertion of single RHPs into the lipid bilayers. It also results in bilayer-spanning segments containing polar monomers that promote the formation of hydrogen-bonded chains15,16 for proton transport. Our study demonstrates the importance of the adaptability that is enabled by statistical similarity among RHP chains and of the modularity provided by the chem. diversity of monomers, to achieve uniform behavior in heterogeneous systems. Our results also validate statistical randomness as an unexplored approach to realize protein-like behavior at the single-polymer-chain level in a predictable manner. This study involved multiple reactions and reactants, such as (2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate (cas: 26662-94-2Related Products of 26662-94-2).
(2R,9Z)-1-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)-3-(palmitoyloxy)propan-2-yl oleate (cas: 26662-94-2) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 26662-94-2
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Ester – an overview | ScienceDirect Topics