Anti-Angiogenic Effect of Cantharellus cibarius Extracts, its Correlation with Lipoxygenase Inhibition, and Role of the Bioactives Therein was written by Marathe, Sandesh J.;Hamzi, Wahiba;Bashein, Abdulla M.;Deska, Jan;Seppanen-Laakso, Tuulikki;Singhal, Rekha S.;Shamekh, Salem. And the article was included in Nutrition and Cancer in 2022.SDS of cas: 1731-94-8 The following contents are mentioned in the article:
Angiogenesis is a complex physiol. process that cannot be treated with single agent therapy. Several edible fungi have been known to encompass bioactive compounds, and are promising sources of multi-component drugs. One such widely consumed edible fungi is Cantharellus cibarius, which has been explored for its biol. activities. The present study focused on assessing the anti-angiogenic activity of petroleum ether and ethanol extracts of C. cibarius using chick chorioallantoic membrane (CAM) assay. Both the extracts showed a dose-dependent response which was compared with the anti-angiogenic activity of the pos. controls silibinin, and lenalidomide. The extracts were also studied for their lipoxygenase (LOX) inhibitory potential and compared to ascorbic acid as the pos. control. The IC50 values of the petroleum ether extract, ethanol extract, and ascorbic acid for LOX inhibition assay were 135.4, 113.1, and 41.5 渭g/mL, resp. Although both the extracts showed similar responses in CAM assay, ethanol extract proved to be more potent in LOX inhibition assay. Finally, the extracts were investigated for their chem. composition using GC-MS. A correlation between LOX inhibition and anti-angiogenic potential was established at the mol. level. A meticulous literature search was carried out to correlate the biochem. composition of the extracts to their anti-angiogenic activity. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8SDS of cas: 1731-94-8).
Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.SDS of cas: 1731-94-8
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