Metabolic, organoleptic and transcriptomic impact of Saccharomyces cerevisiae genes involved in the biosynthesis of linear and substituted esters was written by Marullo, Philippe;Trujillo, Marine;Viannais, Remy;Hercman, Lucas;Guillaumie, Sabine;Colonna-Ceccaldi, Benoit;Albertin, Warren;Barbe, Jean-Christophe. And the article was included in International Journal of Molecular Sciences in 2021.Computed Properties of C10H20O2 The following contents are mentioned in the article:
Esters constitute a broad family of volatile compounds impacting the organoleptic properties of many beverages, including wine and beer. They can be classified according to their chem. structure. Higher alc. acetates differ from fatty acid Et esters, whereas a third group, substituted Et esters, contributes to the fruitiness of red wines. Derived from yeast metabolism, the biosynthesis of higher alc. acetates and fatty acid Et esters has been widely investigated at the enzymic and genetic levels. As previously reported, two pairs of esterases, resp. encoded by the paralogue genes ATF1 and ATF2, and EEB1 and EHT1, are mostly involved in the biosynthesis of higher alc. acetates and fatty acid Et esters. These esterases have a moderate effect on the biosynthesis of substituted Et esters, which depend on mono-acyl lipases encoded by MGL2 and YJU3. The functional characterization of such genes helps to improve our understanding of substituted ester metabolism in the context of wine alc. fermentation In order to evaluate the overall sensorial impact of esters, we attempted to produce young red wines without esters by generating a multiple esterase-free strain (未atf1, 未atf2, 未eeb1, and 未eht1). Surprisingly, it was not possible to obtain the deletion of MGL2 in the 未atf1/未atf2/未eeb1/未eht1 background, highlighting unsuspected genetic incompatibilities between ATF1 and MGL2. A preliminary RNA-seq anal. depicted the overall effect of the 未atf1/未atf2/未eeb1/未eht1 genotype that triggers the expression shift of 1124 genes involved in nitrogen and lipid metabolism, but also chromatin organization and histone acetylation. These findings reveal unsuspected regulatory roles of ester metabolism in genome expression for the first time. This study involved multiple reactions and reactants, such as Octyl acetate (cas: 112-14-1Computed Properties of C10H20O2).
Octyl acetate (cas: 112-14-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Computed Properties of C10H20O2
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics