Fe3O4/ZnO/MWCNTs magnetic nanocomposites promoted synthesis of new chromeno pyrano [2,3-d]thiazins: Investigation of antioxidant and antibacterial activities was written by Dadashi, Hani;Hajinasiri, Rahimeh;Hossaini, Zinatossadat. And the article was included in Applied Organometallic Chemistry in 2021.Application In Synthesis of Isopropylisothiocyanate The following contents are mentioned in the article:
The Fe3O4/ZnO/MWCNTs magnetic nanocomposites as a high-performance organometallic catalyst were employed for the preparation of new chromeno pyrano [2,3-d]thiazins derivatives I (R = Me, OMe, NO2; R1 = H, Me; R2 = CH3, C2H5, C6H5, 4-CH3C6H4, 4-CH3OC6H4, 4-O2NC6H4; R3 = CH(CH3)2, C2H5, C6H5, 4-CH3C6H4, 4-CH3OC6H4, 4-O2NC6H4; X = O, NH) in high yields via the five component reactions of 2-hydroxyacetophenones like 1-(2-Hydroxy-3-methyl-5-nitrophenyl)ethanone, 1-(2-Hydroxy-5-methylphenyl)ethan-1-one, 1-(2-Hydroxy-3,5-dimethylphenyl)ethanone and 1-(2-hydroxy-5-methoxyphenyl)ethanone, di-Me carbonate, aldehydes R2CHO, malononitrile or Et 2-cyanoacetate, and isothiocyanates R3NCS in ionic liquid at room temperature The Fe3O4/ZnO/MWCNTs MNCs were synthesized using ionic liquid [OMIM]Br as a stabilizer and soft template. As well Fe3O4/ZnO/MWCNTs MNCs show a good improvement in the yield of the product and showed significant reusable ability. Due to having NH group in synthesized compounds, antioxidant property of some synthesized compounds I was investigated by diphenyl-picrylhydrazine (DPPH) radical trapping and power of ferric reduction experiment Furthermore, the disk diffusion test on Gram-pos. and Gram-neg. bacteria is utilized for investigation of antimicrobial activity of some chromeno pyrano [2,3-d]thiazins I. The achieved outcomes of this experiment demonstrate that these synthesized compounds I could prevent growth of bacteria. Short time of reaction, high yields of product, easy separation of catalyst, and products are some benefits of this process. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Application In Synthesis of Isopropylisothiocyanate).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application In Synthesis of Isopropylisothiocyanate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics