In 2019,Tetrahedron included an article by Zhang, Jiaxing; Zhao, Gang. Computed Properties of C8H14O4. The article was titled 《Enantioselective Mannich reaction of γ-malonate-substituted α,β-unsaturated esters with N-Boc imines catalyzed by chiral bifunctional thiourea-phosphonium salts》. The information in the text is summarized as follows:
A novel enantioselective Mannich reaction of γ-malonate-substituted α,β-unsaturated esters with N-protected aryl aldimines was realized by using asym. phase-transfer catalysis (APTC). With amino acid-derived bifunctional thiourea-phosphonium salts as a catalyst, a series of enantio-enriched Mannich products were synthesized under very mild and simple reaction conditions with high yields and enantioselectivities. In addition to this study using Diethyl 2-methylmalonate, there are many other studies that have used Diethyl 2-methylmalonate(cas: 609-08-5Computed Properties of C8H14O4) was used in this study.
Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Computed Properties of C8H14O4
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics