Lan, Jin; Le, Zhanggao; Li, Hongxia; Meng, Jia; Gong, Bozhen; Xie, Zongbo published their research in Molecular Catalysis on December 31 ,2020. The article was titled 《Selective synthesis of functionalized quinazolinone derivatives via biocatalysis》.Related Products of 30414-53-0 The article contains the following contents:
A novel and efficient biocatalyzed methodol. for the construction of functionalized quinazolinone derivatives via tandem / hydrolysis / decarboxylation / cyclization and transesterification reactions has been developed that works with a variety of 2-aminobenzamide and β-dicarbonyl compounds This method requires mild conditions, and has demonstrated high catalytic activity, excellent yields, excellent chemoselectivity, and a broad substrate scope. Addnl., biocatalyzed decarboxylation does not require high temperatures or light activation, giving it a substantial advantage over alternative techniques. Most importantly, it offers a new example for the exploration of simple, convenient, and environmentally friendly synthetic routes utilizing enzymes in organic chem.Methyl 3-oxovalerate(cas: 30414-53-0Related Products of 30414-53-0) was used in this study.
Methyl 3-oxovalerate(cas: 30414-53-0) belongs to ketone compounds. Ketone compounds have important physiological properties. They are found in several sugars and in compounds for medicinal use, including natural and synthetic steroid hormones. Molecules of the anti-inflammatory agent cortisone contain three ketone groups.Related Products of 30414-53-0
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