Tsuji, Hiroaki; Suzuki, Koki; Kawatsura, Motoi published an article in 2021. The article was titled ãRuthenium-catalyzed stereospecific benzylic alkylation of optically active benzyl esters with malonate nucleophilesã? and you may find the article in Tetrahedron Letters.Reference of Diethyl 2-methylmalonate The information in the text is summarized as follows:
Herein, the study for the ruthenium-catalyzed benzylic alkylation of chiral benzyl esters with malonates as a carbon nucleophile was described. A combination of [Cp*RuCl2]2 and picolinic acid found to be effective for the title reaction, provided the chiral benzylic alkylation products with retention of stereochem. of the starting material. The ruthenium catalysis was proceed via a double inversion mechanism was proposed. In the experiment, the researchers used Diethyl 2-methylmalonate(cas: 609-08-5Reference of Diethyl 2-methylmalonate)
Diethyl 2-methylmalonate(cas: 609-08-5) belongs to aliphatic hydrocarbons. Aliphatic hydrocarbons belong to the most abundant fraction in crude oil. Aliphatics molecules are linear or branched open-chain structures such as n-alkanes, isoalkanes, cycloalkanes (naphthenes), terpenes and steranes.Reference of Diethyl 2-methylmalonate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics