On February 4, 1999, Hardy, Jean-Claude; Bouquerel, Jean; Nemecek, Patrick; Peyronel, Jean-Francois published a patent.Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate The title of the patent was Preparation of thiazolobenzazepines and analogs as anticonvulsants and glutamate antagonists. And the patent contained the following:
Title compounds [I; R2 = H or alkyl; R6R3 = (CH2)4, (CH2)3CO, (CH2)3O, etc.; R7 = polyfluoroalkyl(oxy); Z = S or Se] were prepared Thus, N-protected Et 2-amino-5-trifluoromethoxybenzoate was N-alkylated by Br(CH2)3CO2Et and the product cyclized to give, in 3 addnl. steps, benzazepine II which was cyclocondensed with KSCN to give I [R2 = H, R6R3 = CH(OH)(CH2)3, R7 = OCF3, Z = S]. Data for biol. activity of I were given. The experimental process involved the reaction of tert-Butyl (4-(trifluoromethyl)phenyl)carbamate(cas: 141940-37-6).Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate
The Article related to thiazolobenzazepine preparation anticonvulsant glutamate antagonist, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Recommanded Product: tert-Butyl (4-(trifluoromethyl)phenyl)carbamate
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